《Science of The Total Environment》杂志刊登“确定南印度高氟区域饮用水中最适宜的氟浓度”

作  者：Gopalan Viswanathan, A. Jaswanth, S. Gopalakrishnan, S. Siva ilango, G. Aditya

刊  物：《Science of The Total Environment》，2009年，407卷第20期，5298-5307页

关键词：氟中毒；适宜氟浓度；摄入总氟量；骨氟；社区氟中毒指数；回归分析

摘  要：饮用水中的氟离子对人体健康既有益又有弊。通过饮水摄入生物利用度超过90%的大量氟化物，将导致氟中毒的蔓延。本研究的目的是由饮水中氟化物组成、其他水质参数、氟中毒蔓延、以及被认为骨骼中氟化物积累不同途径的饮水、食物和茶、咖啡这样饮料，来预测高氟区域饮用水中氟化物适宜浓度，通过回归分析比较高氟和非高氟区域具有的相同地质特征。研究结果表明，饮用水中氟化物的浓度超过1.33mg/L时导致社区氟中毒指标（CFI）超过0.6，超过一个适合的指标值氟中毒被认为是一个公共健康问题。水中氟浓度和骨骼中氟含量的回归图显示，在2~3年内水氟浓度每增加0.5mg/L将导致骨氟浓度提高52mg/kg。此外，饮用水氟化浓度大于0.65mg/L时，将导致每天摄入的总氟量超过中毒物质疾病登记署对成年人建议的最佳氟化物摄入水平（4mg）。由此可知，为避免氟中毒，建议南印度高氟区居民饮用氟化物浓度为0.5-0.65mg/L的饮用水。

Determining the optimal fluoride concentration in drinking water for fluoride endemic regions in South India

Authors: Gopalan Viswanathan, A. Jaswanth, S. Gopalakrishnan, S. Siva ilango, G. Aditya

Journal: Science of The Total Environment, Volume 407, Number 20 (2009), 5298-5307

Key words: Fluorosis; Optimal fluoride level; Total fluoride intake; Bone fluoride; Community fluorosis index; Regression analysis

Abstract: Fluoride ion in drinking water is known for both beneficial and detrimental effects on health. The prevalence of fluorosis is mainly due to the intake of large quantities of fluoride through drinking water owing to more than 90% bioavailability. The objective of this study is to predict optimal fluoride level in drinking water for fluoride endemic regions by comprising the levels of fluoride and other water quality parameters in drinking water, prevalence of fluorosis, fluoride intake through water, food and beverages such as tea and coffee and also considering the progressive accumulation of fluoride in animal bones, by comparing with non fluoride endemic areas comprise of the same geological features with the aid of regression analysis. Result of this study shows that increase of fluoride level above 1.33 mg/L in drinking ater increases the community fluorosis index (CFI) value more than 0.6, an optimum index value above which fluorosis is considered to be a public health problem. Regression plot between water fluoride and bone fluoride levels indicates that, every increase of 0.5 mg/L unit of water fluoride level increases the bone fluoride level of 52 mg/kg unit within 2 to 3 years. Furthermore, the consumption of drinking water containing more than 0.65 mg/L of fluoride can raise the total fluoride intake per day more than 4 mg, which is the optimum fluoride dose level recommended for adults by the Agency for Toxic Substances and Disease Registry. From the result, the people in fluoride endemic areas in South India are advised to consume drinking water with fluoride level within the limit of 0.5 to 0.65 mg/L to avoid further fluorosis risk.

原文链接：http://www.springerlink.com/content/k7q7x11326205748/

翻译：孙瑞刚；审核：陈康宁